TIMI risk score for Unstable angina / Non ST Elevation Myocardial Infarction

 

TIMI stands for “Thrombolysis in Myocardial Infarction”. TIMI Trial is a study group that has conducted several trials mainly on the cardiovascular disease as general. The study also focuses on percutaneous coronary intervention and thrombolysis. In Acute coronary syndrome, accurate risk stratification is important to guide us for the appropriate therapy. The TIMI risk score can be used as a tool to use in managing people with possible acute coronary syndrome. It is a lot better compare to ECG changes and troponin alone.

TIMI risk score for Unstable angina / Non ST Elevation MI

 

Risk factor Score
Age 65 years old or more 1
Present of 3 risk factors for CAD (Coronary Artery Disease) or more 1
Patient is a know case of CAD (stenosis ? 50%) 1
Aspirin is used for the past 7 days 1
Patient have severe angina ( 2 or more episodes within 24 hours) 1
ST changes ? 0.5mm 1
Positive cardiac marker 1

 

The score is between 0-7. The higher the score means the risk is greater and the patient should have an early intervention.

 

TIMI risk score Risk at 14 days of all-cause mortality, new or recurrent MI, or severe recurrent ischemia requiring urgent revascularization.
1 5%
2 8%
3 13%
4 20%
5 26%
6 – 7 41%

 

Risk factors for CAD:

  • Family history of CAD
  • Hypertension
  • Hypercholesterolaemia
  • Diabetes mellitus
  • Current smoker

 

Related topic:

 

Reference:

  1. Available at : http://www.mdcalc.com/timi-risk-score-for-uanstemi
  2. http://en.wikipedia.org/wiki/TIMI
  3. Available at : http://qjmed.oxfordjournals.org/cgi/content/abstract/99/2/81

Killip classification

 

Acute myocardial infarction is associated with high mortality. Killip classification is used to measure the risk stratification of patients with acute myocardial infarction (heart attack). The idea is those with low killip classification is less likely to die within 30 days after the acute attack. Those with killip class I should be considered for early beta blockade to reduce the mortality rate.

 

Class Character Mortality within 30 days
I No clinical signs of heart failure. No pulmonary edema or lung congestion 6%
II Moderate left heart failure (bibasilar lung crepitation/rales, S3 gallop, tacypnoea, raised JVP, edema 17%
III Severe left heart failure with frank pulmonary congestion (pulmonary edema) 38%
IV This patient already in cardiogenic shock and hypotension (systolic blood pressure < 90mmHg). There is evidence of  peripheral vasoconstriction (present of cyanosis, confusion, oliguria or sweating) 81%

 

JVP=Jugular Venous Pressure

Oliguria = reduce urine output

 

Related topic:

 

Reference:

  1. David S. Smith. Field Guide to Bedside Diagnosis. 2nd edition. Lippincott Williams and Wilkins. 2007.
  2. Available at : http://wapedia.mobi/en/Killip_class